David S. Geller, MD

Vice Chairman, Strategy and Innovation
Co-Director, Orthopedic Oncology
Associate Director, Musculoskeletal Oncology Laboratory
Professor, Orthopedic Surgery and Pediatrics

David S. Geller, MD - Vice Chairman, Strategy and Innovation,  Co-Director, Orthopedic Oncology, Associate Director, Musculoskeletal Oncology Laboratory,  Professor, Orthopedic Surgery and Pediatrics - Orthopedic Oncology
  • Montefiore Greene Medical Arts Pavilion
    3400 Bainbridge Avenue
    Bronx, NY 10467-2404

  • Orthopedic Oncology

  • (718) 920-2060


David S. Geller is a board-certified orthopedic oncologist who specializes in the treatment of both pediatric and adult patients with bone and soft-tissue tumors. He has been a full-time faculty member at Montefiore since 2006. He is an Associate Professor of Orthopedic Surgery and Pediatrics at our Albert Einstein College of Medicine.

Dr. Geller is known for his expertise in musculoskeletal tumor surgery, with specific experience in bone and soft-tissue sarcomas, such as osteosarcoma, Ewing’s sarcoma, liposarcoma and synovial sarcoma. He has extensive experience in managing patients with metastatic carcinoma of the bone as well. He routinely offers limb-salvage surgery using a wide array of reconstructive tools.

Dr. Geller earned his medical degree from Tel Aviv University’s Sackler School of Medicine and completed an orthopedic surgery residency at Montefiore. He received his fellowship training from the Harvard Combined Orthopedic Oncology Program, which included Massachusetts General Hospital, Boston Children’s Hospital, and Beth Israel Deaconess Medical Center.

Dr. Geller serves as the Associate Director of the Musculoskeletal Oncology Research Laboratory at Montefiore. He leads numerous translational research efforts designed to investigate the pathophysiology and molecular mechanisms of bone and soft tissue cancers. He is interested in improved surgical techniques and novel therapeutic approaches for primary malignant bone tumors. He is actively involved in collaborative clinical trials both nationally and internationally.

Dr. Geller is an active member of the American Academy of Orthopedic Surgeons, Muskuloskeletal Tumor Society, Connective Tissue Oncology Society, Children’s Oncology Group, American Orthopedic Association, and the American Association for Cancer Research.

Research Focus

Osteosarcoma, with an interest in innovative treatment strategies for both local disease control and metastatic disease; evaluation of expression patterns in osteosarcoma and surgical margins using a xenograft osteosarcoma murine model; the functional role of bone morphogenetic proteins in osteosarcoma surgery; use of intraoperative navigation techniques for tumor surgery; tumorigenesis of osteosarcoma

Clinical Focus

Orthopedic oncology, orthopedic surgery, bone and soft tissue sarcomas, benign bone and soft-tissue tumors, metastatic carcinoma on the bone

Education & Training

  • Medical School

    Sackler School of Medicine, New York

  • Residency

    Montefiore Medical Center

  • Fellowship

    Massachusetts General Hospital

Published Research

See all

Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma

Pratistha Koirala; Michael E. Roth; Jonathan Gill; Sajida Piperdi; Jordan M. Chinai; David S. Geller; Bang H. Hoang; Amy Park; Michael A. Fremed; Xingxing Zang; Richard Gorlick

David S. Geller Dec 2021

Current and future therapeutic approaches for osteosarcoma

Douglas J. Harrison; David S. Geller; Jonathan D. Gill; Valerae O. Lewis; Richard Gorlick

David S. Geller Dec 2021

Distally based anterolateral thigh flap

Mikhail Bekarev; Abraham M. Goch; David S. Geller; Evan S. Garfein

David S. Geller Dec 2021

Transcriptional Profiling Identifies the Signaling Axes of IGF and Transforming Growth Factor-β as Involved in the Pathogenesis of Osteosarcoma

Rui Yang; Sajida Piperdi; Yue Zhang; Wei Zhu; Neophytos Neophytou; Bang H. Hoang; Gary Mason; David Geller; Howard Dorfman; Paul A. Meyers; John H. Healey; Donald G. Phinney; Richard Gorlick

David S. Geller Dec 2021

β-catenin does not confer tumorigenicity when introduced into partially transformed human mesenchymal stem cells

Sajida Piperdi; Lukas Austin-Page; David Geller; Manpreet Ahluwalia; Sarah Gorlick; Jonathan Gill; Amy Park; Wendong Zhang; Nan Li; So Hak Chung; Richard Gorlick

David S. Geller Dec 2021

Insulin-like growth factor 1 receptor and response to anti-IGF1R antibody therapy in osteosarcoma

Yu Cao; Michael Roth; Sajida Piperdi; Kristofer Montoya; Rebecca Sowers; Pulivarthi Rao; David Geller; Peter Houghton; E. Anders Kolb; Jonathan Gill; Richard Gorlick

David S. Geller Dec 2021

HHLA2, a member of the B7 family, is expressed in human osteosarcoma and is associated with metastases and worse survival

Pratistha Koirala; Michael E. Roth; Jonathan Gill; Jordan M. Chinai; Michelle R. Ewart; Sajida Piperdi; David S. Geller; Bang H. Hoang; Yekaterina V. Fatakhova; Maya Ghorpade; Xingxing Zang; Richard Gorlick

David S. Geller Dec 2021


  • Alan Darby Case Report of the Year Award Skeletal Radiology [ 2009 ]

  • Teacher of the Year Orthopedic Surgery [ 2010 ]

  • Alumni of the Year Orthopedic Surgery [ 2012 ]

  • Castle Connolly Top Doctors New York Metro Area

  • New Patient Appointments

    Seeing us is easy. Simply fill out our online form, and we’ll contact you within 24 hours to schedule an appointment within the next seven days.

    Request an appointment
  • Physician Referrals

    Montefiore embraces a collaborative approach. If you have a patient who could benefit from our services, please reach out.

    Refer a patient
  • Contact Us

    Have any general questions or concerns? Contact us by phone or email.